Letter to the Editors regarding "10% body weight (gain) change as criterion for the maximum tolerated dose: A critical analysis".

Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: SMC is on the editorial board of Regulatory Toxicology and Pharmacology. The opinions expressed in this letter are personal and do not represent a position of the journal. CS is currently chairman of the Human Health Expert Group of CropLife Europe. CC: The information in this document has been funded in part by the U.S. Environmental Protection Agency. It has been subjected to review by the Center for Computational Toxicology and Exposure and approved for publication. Approval does not signify that the contents reflect the views of the Agency, nor does mention of trade names or commercial products constitute endorsement or recommendation for use.