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Diabetes characteristics and long-term management needs in diabetic TB patients.
- Source :
-
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease [Int J Tuberc Lung Dis] 2023 Feb 01; Vol. 27 (2), pp. 113-120. - Publication Year :
- 2023
-
Abstract
- BACKGROUND: Diabetes mellitus (DM) is common among patients with TB. We assessed DM characteristics and long-term needs of DM-TB patients after completing TB treatment. METHODS: Newly diagnosed TB patients with DM were recruited for screening in a randomised clinical trial evaluating a simple algorithm to improve glycaemic control during TB treatment. DM characteristics, lifestyle and medication were compared before and after TB treatment and 6 months later. Risk of cardiovascular disease (CVD), albuminuria and neuropathy were assessed after TB treatment. RESULTS: Of 218 TB-DM patients identified, 170 (78%) were followed up. Half were males, the mean age was 53 years, 26.5% were newly diagnosed DM. High glycated haemoglobin at TB diagnosis (median 11.2%) decreased during TB treatment (to 7.4% with intensified management and 8.4% with standard care), but this effect was lost 6 months later (9.3%). Hypertension and dyslipidemia contributed to a high 10-year CVD risk (32.9% at month 6 and 35.5% at month 12). Neuropathy (33.8%) and albuminuria (61.3%) were common. After TB treatment, few patients used CVD-mitigating drugs. CONCLUSION: DM in TB-DM patients is characterised by poor glycaemic control, high CVD risk, and nephropathy. TB treatment provides opportunities for better DM management, but effort is needed to improve long-term care.
- Subjects :
- Female
Humans
Male
Middle Aged
Albuminuria diagnosis
Albuminuria epidemiology
Algorithms
Glycated Hemoglobin
Cardiovascular Diseases epidemiology
Cardiovascular Diseases etiology
Cardiovascular Diseases prevention & control
Diabetes Mellitus
Tuberculosis drug therapy
Tuberculosis epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1815-7920
- Volume :
- 27
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
- Publication Type :
- Academic Journal
- Accession number :
- 36853103
- Full Text :
- https://doi.org/10.5588/ijtld.22.0367