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Ultrasonographic and Functional Features of Symptomatic Uncomplicated Diverticular Disease.

Ultrasonographic and Functional Features of Symptomatic Uncomplicated Diverticular Disease.

Authors :
Maconi G
Dell'Era A
Flor N
De Silvestri A
Lavazza A
Ardizzone S
Bassotti G
Source :
Clinical and translational gastroenterology [Clin Transl Gastroenterol] 2023 Jun 01; Vol. 14 (6), pp. e00580. Date of Electronic Publication: 2023 Jun 01.
Publication Year :
2023

Abstract

Introduction: To evaluate the ability of intestinal ultrasound (IUS) in discriminating symptomatic uncomplicated diverticular disease (SUDD) among patients with abdominal symptoms including irritable bowel syndrome (IBS).<br />Methods: This observational, prospective study included consecutive patients classified into the following categories: (i) SUDD; (ii) IBS; (iii) unclassifiable abdominal symptoms; and (iv) controls, including asymptomatic healthy subjects and diverticulosis. The IUS evaluation of the sigmoid: assessed the presence of diverticula, thickness of the muscularis propria, and IUS-evoked pain, namely the intensity of pain evoked by compression with the ultrasound probe on sigmoid colon compared with an area of the left lower abdominal quadrant without underlying sigmoid colon.<br />Results: We enrolled 40 patients with SUDD, 20 patients with IBS, 28 patients with unclassifiable abdominal symptoms, 10 healthy controls, and 20 patients with diverticulosis. Patients with SUDD displayed significantly ( P < 0.001) greater muscle thickness (2.25 ± 0.73 mm) compared with patients with IBS (1.66 ± 0.32 mm), patients with unclassifiable abdominal pain, and healthy subjects, but comparable with that of patients with diverticulosis (2.35 ± 0.71 mm). Patients with SUDD showed a greater (not significant) differential pain score than other patients. There was a significant correlation between the thickness of the muscularis propria and the differential pain score only for patients with SUDD ( r = 0.460; P : 0.01). Sigmoid diverticula were detected by colonoscopy in 40 patients (42.4%) and by IUS with a sensitivity of 96.0% and a specificity of 98.5%.<br />Discussion: IUS could represent a useful diagnostic tool for SUDD, potentially useful in characterizing the disease and appropriately address the therapeutic approach.<br /> (Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.)

Details

Language :
English
ISSN :
2155-384X
Volume :
14
Issue :
6
Database :
MEDLINE
Journal :
Clinical and translational gastroenterology
Publication Type :
Academic Journal
Accession number :
36892507
Full Text :
https://doi.org/10.14309/ctg.0000000000000580