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The Techniques of Blood Purification in the Treatment of Sepsis and Other Hyperinflammatory Conditions.

Authors :
Berlot G
Tomasini A
Zanchi S
Moro E
Source :
Journal of clinical medicine [J Clin Med] 2023 Feb 21; Vol. 12 (5). Date of Electronic Publication: 2023 Feb 21.
Publication Year :
2023

Abstract

Even in the absence of strong indications deriving from clinical studies, the removal of mediators is increasingly used in septic shock and in other clinical conditions characterized by a hyperinflammatory response. Despite the different underlying mechanisms of action, they are collectively indicated as blood purification techniques. Their main categories include blood- and plasma processing procedures, which can run in a stand-alone mode or, more commonly, in association with a renal replacement treatment. The different techniques and principles of function, the clinical evidence derived from multiple clinical investigations, and the possible side effects are reviewed and discussed along with the persisting uncertainties about their precise role in the therapeutic armamentarium of these syndromes.

Details

Language :
English
ISSN :
2077-0383
Volume :
12
Issue :
5
Database :
MEDLINE
Journal :
Journal of clinical medicine
Publication Type :
Academic Journal
Accession number :
36902510
Full Text :
https://doi.org/10.3390/jcm12051723