Lessons from a pandemic.

Several interventions have been used around the world trying to contain the SARS-CoV-2 pandemic, such as quarantine, prohibition of mass demonstrations, isolation of sick people, tracing of virus carriers, semi-containment, promotion of barrier gestures, development of rapid self-tests and vaccines among others. We propose a simple model to evaluate the potential impact of such interventions. A model for the reproduction number of an infectious disease including three main contexts of infection (indoor mass events, public indoor activities and household) and seven parameters is considered. We illustrate how these parameters could be obtained from the literature or from expert assumptions, and we apply the model to describe 20 scenarios that can typically occur during the different phases of a pandemic. This model provides a useful framework for better understanding and communicating the effects of different (combinations of) possible interventions, while encouraging constant updating of expert assumptions to better match reality. This simple approach will bring more transparency and public support to help governments to think, decide, evaluate and adjust what to do during a pandemic.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright: © 2022 Eggli, Rousson. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)