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Normative data for macular perimetry using the MP-3 microperimeter in healthy individuals.

Authors :
Rodrigues Neto TDS
Silva Neto EDD
Higashi AH
Megnis BP
Haddad MAO
Monteiro MLR
Zacharias LC
Source :
Arquivos brasileiros de oftalmologia [Arq Bras Oftalmol] 2023 Apr 03. Date of Electronic Publication: 2023 Apr 03.
Publication Year :
2023
Publisher :
Ahead of Print

Abstract

Purpose: Microperimetry has been used for several years as a form of visual function testing in patients with retinal diseases. Normal microperimetry values obtained with microperimeter MP-3 have not yet been fully published, and baseline values for topographic macular sensitivity and correlations with age and sex are needed to establish degrees of impairment. This study aimed to determine values for light sensitivity thresholds and fixation stability using the MP-3 in healthy individuals.<br />Methods: Thirty-seven healthy volunteers (age, 28-68 years), underwent full-threshold microperimetry using a 4-2 (fast) staircase strategy with the standard Goldmann III stimulus size and 68 test points positioned identically to those in the Humphrey Field Analyzer 10-2 test grid. The fixation stability was simultaneously recorded during the microperimetry test. The relationship between global sensitivity and age was calculated using linear regression analysis.<br />Results: Microperimetry was performed on 37 participants (74 eyes). The global mean sensitivity was 29.01 ± 1.44 (range, 26-31) dB. The mean central sensitivity at 2° measured by the MP-3 was 28.5 ± 1.77 dB in the right eye (OD) and 28.75 ± 1.98 dB in the left eye (OS). The total median fixation stability values within 2° and 4° were 80% and 96%, respectively. The linear regression analysis also revealed an age-related global sensitivity decline per year of -0.051 dB ± 0.018 (OD) and -0.078 dB ± 0.021 (OS).<br />Conclusions: Microperimetry performed with the MP-3 allows for an automatic, accurate, and topography-specific examination of retinal sensitivity thresholds. The results of this study provide a normal and age-matched database of MP-3 microperimetry.

Details

Language :
English
ISSN :
1678-2925
Database :
MEDLINE
Journal :
Arquivos brasileiros de oftalmologia
Publication Type :
Academic Journal
Accession number :
37018820
Full Text :
https://doi.org/10.5935/0004-2749.2021-0472