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Vitamin D Status in Osteoporotic and Diabetic Patients and Athletic Healthy Individuals from Northern Greece.

Authors :
Anetakis C
Mitka S
Chatzidimitriou M
Anagnostopoulos K
Eleftheriou P
Lialiaris T
Source :
Reports of biochemistry & molecular biology [Rep Biochem Mol Biol] 2023 Jan; Vol. 11 (4), pp. 565-576.
Publication Year :
2023

Abstract

Background: Vitamin D deficiency is recognised as a pandemic in the developed world. However, the importance of prudent sun exposure tends to be overlooked, which is responsible for this pandemic.<br />Methods: We investigated the vitamin D status in 326 adults, 165 females and 161 males: 99 Osteoporosis patients, 53 Type 1 Diabetes patients, 51 Type 2 Diabetes patients, and 123 Athletic Healthy individuals, from Northern Greece, through the measurement of total calcidiol in winter and summer by immunoenzymatic assay.<br />Results: In the Whole Sample 23.31% had severe deficiency, 13.50% mild deficiency, 17.48% insufficiency, and 45.71% adequacy at the end of winter. Mean concentrations differed significantly (p <0.001) between males and females. The prevalence of deficiency in the young was significantly lower than in the middle-aged (p = 0.004) and in the elderly (p <0.001), while it was significantly lower (p = 0.014) in the middle-aged than in the elderly. The best vitamin D status was found in the Athletic Healthy individuals, followed by the Type 1 and Type 2 Diabetic patients, while Osteoporotic patients had the poorest status. The difference in mean concentrations between winter and summer was significant (p <0.001).<br />Conclusions: Vitamin D status deteriorated with increasing age and it was better in males than in females. Our findings suggest that outdoor physical activity in a Mediterranean country can cover the vitamin D needs of the young and the middle-aged, but not of the elderly, without the need for dietary supplements.<br />Competing Interests: No potential conflict of interest was reported by the authors

Details

Language :
English
ISSN :
2322-3480
Volume :
11
Issue :
4
Database :
MEDLINE
Journal :
Reports of biochemistry & molecular biology
Publication Type :
Academic Journal
Accession number :
37131899
Full Text :
https://doi.org/10.52547/rbmb.11.4.565