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Mutagenicity of 1,2-dibromo-3-chloropropane (DBCP) in the mouse spot test.

Authors :
Sasaki YF
Imanishi H
Watanabe M
Sekiguchi A
Moriya M
Shirasu Y
Tutikawa K
Source :
Mutation research [Mutat Res] 1986 Jun; Vol. 174 (2), pp. 145-7.
Publication Year :
1986

Abstract

The spot test with 1,2-dibromo-3-chloropropane (DBCP) was carried out using male PW and female C57BL/6 mice. DBCP induced recessive colour spots in offspring with a significantly high frequency of 2.9%, showing that this chemical is mutagenic for somatic cells of mice in vivo.

Details

Language :
English
ISSN :
0027-5107
Volume :
174
Issue :
2
Database :
MEDLINE
Journal :
Mutation research
Publication Type :
Academic Journal
Accession number :
3713732
Full Text :
https://doi.org/10.1016/0165-7992(86)90106-5