Outcomes of an exercise program in patients with dorsal or volar midcarpal laxity: a cohort study of 213 patients.

Purpose: Describing the outcomes of an exercise program on wrist and hand function for patients with midcarpal instability (MCI).
Materials and Methods: This study has a prospective cohort design. Two hundred and thirteen patients with MCI were included. The intervention was a 3-month exercise program consisting of hand therapy and home exercises. The primary outcome was perceived wrist and hand function evaluated with the Patient-Rated Wrist/Hand Evaluation (PRWHE) three months after treatment onset. Secondary outcomes were conversion to surgery, pain, and satisfaction with treatment results.
Results: PRWHE total scores improved from 51 ± 19 (mean ± SD) to 33 ± 24 at 3 months (95% CI: 36-30, p  < 0.001). All visual analog scales for pain demonstrated clinically relevant improvements at 6 weeks and 3 months ( p  < 0.001). At 3 months, 81% of the participants would undergo the treatment again. After a median follow-up of 2.8 years, 46 patients (22%) converted to surgery.
Conclusions: We found clinically relevant improvements in hand and wrist function and pain. Most participants would undergo treatment again and 78% of the participants did not convert to surgery. Hence, non-invasive treatment should be the primary treatment choice for patients with MCI.