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Predictors of premature termination and completion of randomized controlled trials.

Authors :
Soletti GJ
Audisio K
Cancelli G
Rahouma M
Dimagli A
Harik L
Olaria RP
Alzghari T
An KR
Polk H
Lia H
Tam DY
Fremes SE
Gaudino M
Source :
Contemporary clinical trials [Contemp Clin Trials] 2023 Jul; Vol. 130, pp. 107219. Date of Electronic Publication: 2023 May 06.
Publication Year :
2023

Abstract

Randomized clinical trials (RCTs) have a key role in progressing biomedical research and guiding clinical decision making, but premature termination remains high (up to 30%), raising concerns regarding funding expenditure and resource allocation. This brief report sought to identify variables associated with RCTs' premature termination and completion.<br />Competing Interests: Declaration of Competing Interest The authors declare no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.<br /> (Copyright © 2023 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1559-2030
Volume :
130
Database :
MEDLINE
Journal :
Contemporary clinical trials
Publication Type :
Academic Journal
Accession number :
37156372
Full Text :
https://doi.org/10.1016/j.cct.2023.107219