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Prevalence and Natural History of Segmental Colitis Associated With Diverticulosis.

Authors :
Tursi A
Piovani D
Brandimarte G
Di Mario F
Elisei W
Picchio M
Allegretta L
Annunziata ML
Bafutto M
Bassotti G
Bianco MA
Colucci R
Conigliaro R
Dumitrascu DL
Escalante R
Ferrini L
Forti G
Franceschi M
Graziani MG
Lammert F
Latella G
Maconi G
Compare D
Nardone G
Camara De Castro Oliveira L
Chaves Oliveira E
Papagrigoriadis S
Pietrzak A
Pontone S
Stundiene I
Pranzo G
Reichert MC
RodinĂ² S
Regula J
Scaccianoce G
Scaldaferri F
Vassallo R
Zampaletta C
Zullo A
Spaziani E
Bonovas S
Papa A
Danese S
Source :
The American journal of gastroenterology [Am J Gastroenterol] 2023 Nov 01; Vol. 118 (11), pp. 2088-2092. Date of Electronic Publication: 2023 Jun 14.
Publication Year :
2023

Abstract

Introduction: We assessed the prevalence and clinical outcomes of segmental colitis associated with diverticulosis (SCAD) in patients with newly diagnosed diverticulosis.<br />Methods: A 3-year international, multicenter, prospective cohort study was conducted involving 2,215 patients.<br />Results: SCAD diagnosis was posed in 44 patients (30 male patients; median age: 64.5 years; prevalence of 1.99%, 95% confidence interval, 1.45%-2.66%). Patients with SCAD types D and B showed worse symptoms, higher fecal calprotectin values, needed more steroids, and reached less likely complete remission.<br />Discussion: Although SCAD generally had a benign outcome, types B and D were associated with more severe symptoms and worse clinical course.<br /> (Copyright © 2023 by The American College of Gastroenterology.)

Details

Language :
English
ISSN :
1572-0241
Volume :
118
Issue :
11
Database :
MEDLINE
Journal :
The American journal of gastroenterology
Publication Type :
Academic Journal
Accession number :
37314163
Full Text :
https://doi.org/10.14309/ajg.0000000000002362