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Association between the copper/selenium ratio and the immune response to SARS-CoV-2 infection.
- Source :
-
Biomarkers in medicine [Biomark Med] 2023 Mar; Vol. 17 (6), pp. 307-317. Date of Electronic Publication: 2023 Jun 20. - Publication Year :
- 2023
-
Abstract
- Aim: To assess the association serum levels of selenium (Se) and copper (Cu) with symptoms and IgG immune response to SARS-CoV-2. Patients & methods/materials: Blood samples and nasopharyngeal swabs were obtained from 126 COVID-19 patients with mild and severe symptoms. The serum levels of Cu and Se were measured by atomic-absorption spectrophotometry. Results & conclusion: Mean Se was higher in patients with mild symptoms and IgG nonresponders, whereas mean Cu was higher in patients with severe symptoms and IgG responders. The Cu/Se ratio was lower in patients with no IgG responses to infection and mild symptoms versus IgG responders with severe symptoms. These results suggest the Cu/Se ratio as a nutritional biomarker of severity and IgG immune response in COVID-19 patients.
Details
- Language :
- English
- ISSN :
- 1752-0371
- Volume :
- 17
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Biomarkers in medicine
- Publication Type :
- Academic Journal
- Accession number :
- 37338262
- Full Text :
- https://doi.org/10.2217/bmm-2022-0530