Brain tumors on slice: A novel platform for personalized therapeutic screening.

Authors :: Sun Y
Wang X
Ming GL
Song H
Source :: Cell reports. Medicine [Cell Rep Med] 2023 Jun 20; Vol. 4 (6), pp. 101059.
Publication Year :: 2023
Abstract: Mann and Zhang et al. developed a robust ex vivo slice culture platform consisting of resected patient high- and low-grade glioma tissue engrafted onto rat organotypic brain slices, and interrogated tumor responses to clinically relevant therapeutics with a novel treatment-response algorithm.<br />Competing Interests: Declaration of interests The authors declare no competing interests.<br /> (Copyright © 2023 The Author(s). Published by Elsevier Inc. All rights reserved.)