Assessment of intrafraction motion for spine and non-spine bone metastases treated with image-guided stereotactic body radiotherapy without 6 degrees-of-freedom couch correction.

Stereotactic body radiotherapy (SBRT) planning target volume (PTV) margins are influenced by multiple factors. Data is limited on intrafraction motion in bone SBRT, particularly non-spine lesions. We analyzed intrafraction motion in bone SBRT patients treated on a standard treatment couch without 6 degrees-of-freedom (6-DOF) correction. Extracranial bone SBRT patients were included. Patients were treated using two volumetric-modulated arcs and targets were localized using daily cone-beam computed tomography (CBCT) prior to each arc. Alignments between the first and second CBCT images yielded intrafraction positional shift values used to compute translational 3-dimensional vector shifts. 125 fractions from 43 patients were reviewed. Median vector shift for all SABR fractions was 0.7 mm (range 0-6.6 mm); spine 0.7 mm (range:0-2.3 mm) and non-spine 0.9 mm (range:0-6.6 mm). Of the 125 fractions, 95% had IFM vectors within the prescribed PTV margin. Intrafraction motion is small for bone SBRT patients treated on a standard couch without 6-DOF correction capabilities. Intrafraction motion was slightly larger for non-spine sites and may require treatment with larger PTV margins than spine cases.
Competing Interests: Authors’ disclosure of potential conflicts of interest BM declares honoraria from AstraZeneca outside of the submitted work. The remaining authors declare no potential conflicts.
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