Back to Search Start Over

Y-chromosome in the olfactory neuroepithelium as a potential biomarker of depression in women with male offspring: an exploratory study.

Y-chromosome in the olfactory neuroepithelium as a potential biomarker of depression in women with male offspring: an exploratory study.

Authors :
Álvarez P
Bellosillo B
Colom F
Longarón R
Barrera-Conde M
Fernández-Ibarrondo L
Toll A
Ginés JM
de la Torre R
Pérez-Solá V
Robledo P
Source :
Molecular and cellular biochemistry [Mol Cell Biochem] 2024 Jun; Vol. 479 (6), pp. 1451-1455. Date of Electronic Publication: 2023 Jul 13.
Publication Year :
2024

Abstract

The persistence of fetal cells in the mother (fetal microchimerism (FMc)) has been described in maternal tissues essential to the newborn. FMc is associated with several diseases that start or worsen in pregnancy or postpartum. This exploratory study reports-for the first time-the presence of FMc in the olfactory neuroepithelium (ON) of both healthy and depressed women with male offspring. However, depressed women had fewer microchimeric cells (digital PCR). The existence of FMc in the ON could facilitate mother-child bonding. These findings open new pathways to study FMc in the ON, female depression, and mother-child bonding.<br /> (© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)

Details

Language :
English
ISSN :
1573-4919
Volume :
479
Issue :
6
Database :
MEDLINE
Journal :
Molecular and cellular biochemistry
Publication Type :
Academic Journal
Accession number :
37440120
Full Text :
https://doi.org/10.1007/s11010-023-04807-y