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Take my breath away: TAM-ing anti-cancer immunity in hypoxic niches.
- Source :
-
Immunity [Immunity] 2023 Aug 08; Vol. 56 (8), pp. 1704-1706. - Publication Year :
- 2023
-
Abstract
- Hypoxia is a major driver of tumor aggressiveness and therapy resistance in GBM. In this issue of Immunity, Sattiraju et al. functionally link hypoxia with diminished anti-cancer immunity caused by sequestration of immunosuppressive TAMs and CTLs in pseudopalisades in GBM.<br />Competing Interests: Declaration of interests The authors declare no competing interests.<br /> (Copyright © 2023 Elsevier Inc. All rights reserved.)
- Subjects :
- Humans
Hypoxia
Cell Line, Tumor
Tumor Microenvironment
Brain Neoplasms pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1097-4180
- Volume :
- 56
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Immunity
- Publication Type :
- Academic Journal
- Accession number :
- 37557077
- Full Text :
- https://doi.org/10.1016/j.immuni.2023.07.010