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Analysis of Erythrocyte Sedimentation Rate Order in Epithelial Ovarian Cancer.

Authors :
Ngadikun
Pradjatmo H
Nugroho KA
Pasala M
Prasetyastuti
Source :
Journal of Cancer [J Cancer] 2023 Jul 16; Vol. 14 (12), pp. 2173-2180. Date of Electronic Publication: 2023 Jul 16 (Print Publication: 2023).
Publication Year :
2023

Abstract

Erythrocyte sedimentation rate order (ESRO), platelet-lymphocyte ratio (PLR), red cell distribution width (RDW), and neutrophil-lymphocyte ratio (NLR) are hematological parameters that reflect the presence of biomarkers in epithelial ovarian cancer (EOC). This study evaluated the best haematological parameter in order to distinguish between EOC patients and healthy individuals. There were a total of 33 patients with EOC as subjects treated in Dr. Sardjito hospital, Yogyakarta, Indonesia and 32 volunteer subjects as controls. Curves of receiver operation, area under the curve, specificity, and sensitivity were estimated. To demonstrate EOC's presence, the ESRO was better than the hematological parameters of RDW, PLR, and NLR (AUC = 0.9245, 0.9010, 0.8351, and 0.7457, respectively; sensitivity and specificity = 83.3 and 90.6; 88.9 and 87.5; 100.0 and 68.8; and 94.4 and 53.1, respectively) at the cut-off points 1,125, 44.2, 163.2, and 2,551. Hence, ESRO is a better parameter to indicate the presence of EOC compared to RDW, PLR and NLR.<br />Competing Interests: Competing Interests: The authors have declared that no competing interest exists.<br /> (© The author(s).)

Details

Language :
English
ISSN :
1837-9664
Volume :
14
Issue :
12
Database :
MEDLINE
Journal :
Journal of Cancer
Publication Type :
Academic Journal
Accession number :
37576394
Full Text :
https://doi.org/10.7150/jca.82941