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Nanotechnology-Based Strategies to Combat Multidrug-Resistant Candida auris Infections.

Authors :
Hetta HF
Ramadan YN
Al-Kadmy IMS
Ellah NHA
Shbibe L
Battah B
Source :
Pathogens (Basel, Switzerland) [Pathogens] 2023 Aug 13; Vol. 12 (8). Date of Electronic Publication: 2023 Aug 13.
Publication Year :
2023

Abstract

An emerging multidrug-resistant pathogenic yeast called Candida auris has a high potential to spread quickly among hospitalized patients and immunodeficient patients causing nosocomial outbreaks. It has the potential to cause pandemic outbreaks in about 45 nations with high mortality rates. Additionally, the fungus has become resistant to decontamination techniques and can survive for weeks in a hospital environment. Nanoparticles might be a good substitute to treat illnesses brought on by this newly discovered pathogen. Nanoparticles have become a trend and hot topic in recent years to combat this fatal fungus. This review gives a general insight into the epidemiology of C. auris and infection. It discusses the current conventional therapy and mechanism of resistance development. Furthermore, it focuses on nanoparticles, their different types, and up-to-date trials to evaluate the promising efficacy of nanoparticles with respect to C. auris .

Details

Language :
English
ISSN :
2076-0817
Volume :
12
Issue :
8
Database :
MEDLINE
Journal :
Pathogens (Basel, Switzerland)
Publication Type :
Academic Journal
Accession number :
37623993
Full Text :
https://doi.org/10.3390/pathogens12081033