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seco -1-Azacubane-2-carboxylic acid-Amide Bond Comparison to Proline.

Authors :
Fahrenhorst-Jones T
Kong D
Burns JM
Pierens GK
Bernhardt PV
Savage GP
Williams CM
Source :
The Journal of organic chemistry [J Org Chem] 2023 Sep 15; Vol. 88 (18), pp. 12867-12871. Date of Electronic Publication: 2023 Aug 30.
Publication Year :
2023

Abstract

seco -1-Azacubane-2-carboxylic acid, an unusual and sterically constrained amino acid, was found to undergo amide bond formation at both the N- and C-termini using proline based bioactive molecule templates as a concept platform.

Details

Language :
English
ISSN :
1520-6904
Volume :
88
Issue :
18
Database :
MEDLINE
Journal :
The Journal of organic chemistry
Publication Type :
Academic Journal
Accession number :
37647582
Full Text :
https://doi.org/10.1021/acs.joc.3c01264