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Effect of Limb Salvage by Excimer Laser Angioplasty Plus Low-Pressure Balloon Inflation in Chronic Limb-Threatening Ischemia Patients with Infrapopliteal Vessel Disease.
- Source :
-
Acta Cardiologica Sinica [Acta Cardiol Sin] 2023 Sep; Vol. 39 (5), pp. 765-772. - Publication Year :
- 2023
-
Abstract
- Background: Patients with chronic limb-threatening ischemia (CLTI) often exhibit long, diffuse, totally occluded and heavily calcified infrapopliteal (IP) lesions. This study evaluated limb salvage after peripheral excimer laser atherectomy (PELA) plus low-pressure balloon inflation (LPBI) without stent deployment in CLTI patients with severe IP disease.<br />Methods: We retrospectively evaluated 70 consecutive patients with 109 IP vessels who underwent PELA plus LPBI from 2010 to 2013. Technical success was defined as at least one IP straight-line flow being achieved below the malleolus. Binary logistic regression was performed to identify factors associated with 6-month limb salvage.<br />Results: Of the 109 IP vessels, 100 (91.7%) were totally occluded, and none of the patients received a stent. Of the 70 patients, 20% were octogenarians, and 85.8% had a Rutherford-Becker class 5 and 6. The technical success rate was 87.1% and 6-month limb salvage rate was 78.6%. Rutherford score was negatively correlated with clinical success (adjusted odds ratio 0.24; p = 0.028). No immediate major cardiovascular events were recorded during admission.<br />Conclusions: PELA plus LPBI may be a treatment option for complex IP lesions in patients with CLTI. Higher Rutherford class was correlated with a lower 6-month limb salvage rate. However, a large-scale study with a control group is needed to clarify our results.<br />Competing Interests: All the authors declare no conflict of interest.
Details
- Language :
- English
- ISSN :
- 1011-6842
- Volume :
- 39
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Acta Cardiologica Sinica
- Publication Type :
- Academic Journal
- Accession number :
- 37720405
- Full Text :
- https://doi.org/10.6515/ACS.202309_39(5).20230115A