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Difference between remimazolam toluenesulfonic acid and propofol in waking quality and conscious state after general anesthesia.
- Source :
-
Ibrain [Ibrain] 2021 Sep 28; Vol. 7 (3), pp. 171-180. Date of Electronic Publication: 2021 Sep 28 (Print Publication: 2021). - Publication Year :
- 2021
-
Abstract
- Objective: To explore the difference of anesthesia recovery and postoperative conscious state between remimazolam toluenesulfonic acid and propofol after induction and maintenance of general anesthesia.<br />Methods: 104 patients undergoing elective tracheal intubation general anesthesia in our hospital were randomly divided into 2 groups: Remimazolam Toluenesulfonic acid group (Group R) and Propofol group (Group P). MOAA/S score, the modified Aldrete score, recovery index, time point, a state of consciousness, interpretative vital signs and adverse events were monitored at different time.<br />Results: Compared with the Group P, the extubation time and orientation recovery time of the Group R were significantly shorter. When the operation time was less than 1 hour, the MOAA/S score of the Group R was shorter than that of Group P at 5 min and 15 min after the operation. To compare with the Group P, the score of MOAA/S in the Group R increased at 5 min, 20 min and 30 min after the operation. When the operation time was less than or equal to 1 h, the modified Aldrete score in the Group R was slightly higher than that in the Group P at 30 min after extubation. There was no injection pain in the the Group R, and the incidence of hypotension was lower than that of propofol.<br />Conclusion: Compared with Propofol, when the operation time of general anesthesia is more than 1 hour, recovery time of Remimazolam Toluenesulfonic acid is shorter, with more complete and higher-quality recovery.<br />Competing Interests: The authors declared that they have no conflicts of interest to this work.<br /> (© 2021 The Authors. Ibrain published by Affiliated Hospital of Zunyi Medical University and Wiley‐VCH GmbH.)
Details
- Language :
- English
- ISSN :
- 2769-2795
- Volume :
- 7
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Ibrain
- Publication Type :
- Academic Journal
- Accession number :
- 37786798
- Full Text :
- https://doi.org/10.1002/j.2769-2795.2021.tb00081.x