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Plasmid-encoded VCC-1 β-lactamase in a clinical isolate of Aeromonas caviae .
- Source :
-
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2023 Nov 15; Vol. 67 (11), pp. e0070723. Date of Electronic Publication: 2023 Oct 27. - Publication Year :
- 2023
-
Abstract
- V ibrio c holerae c arbapenemase (VCC-1) is a chromosomal encoded class A carbapenemase thus far reported in environmental Vibrio cholerae isolates. Here, we report the first isolation of a bla <subscript>VCC-1</subscript> -carrying Aeromonas caviae from a clinical sample in Israel. The isolate was resistant to all β-lactam agents, including carbapenems. The bla <subscript>VCC-1</subscript> was located on a large plasmid. GC content suggests that the origin of the bla <subscript>VCC-1</subscript> gene is neither Aeromonas nor Vibrio spp. but an unknown progenitor.<br />Competing Interests: The authors declare no conflict of interest.
Details
- Language :
- English
- ISSN :
- 1098-6596
- Volume :
- 67
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Antimicrobial agents and chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 37889006
- Full Text :
- https://doi.org/10.1128/aac.00707-23