Elevated 68 Ga-FAPI-04 Activity Due to Staphylococcus aureus Intracranial Infection.

Abstract: A 37-year-old man was admitted to our hospital after experiencing syncope. An MRI of his head revealed multiple foci of abnormal signal, which could potentially be metastases. The patient then underwent a 68 Ga-FAPI-04 PET/MRI examination, which revealed multiple FAPI-avid foci in the brain. Upon analyzing the cerebrospinal fluid, it was found that the patient had a Staphylococcus aureus infection. The results suggest that 68 Ga-FAPI-04 PET has the potential to be a valuable tool in the visualization of intracranial infectious lesions.
Competing Interests: Conflicts of interest and sources of funding: This work is supported by the “234 Discipline Climbing Plan” of the First Affiliated Hospital of Naval Medical University (grants 2019YPT002 and 2020YPT002). None declared to all authors.
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