Al 2 O 3 -Stabilized Pt Nanozymes: Peroxidase Mimetics and Application in Glucose Detection.

Authors :: Ma Y
Yi S
Gao C
Yang M
Feng D
Ren Y
Ge H
Source :: ChemPlusChem [Chempluschem] 2024 Jul; Vol. 89 (7), pp. e202300609. Date of Electronic Publication: 2023 Dec 13.
Publication Year :: 2024
Abstract: As promising alternatives for natural enzymes, much attention has been paid to nanozymes. And our recent study showed that the medium acid sites on the support are the active sites for the adsorption and oxidation of the substrate. Thus, in this work, due to the abundance of medium acid sites, Al <subscript>2</subscript> O <subscript>3</subscript> was chosen as the support to prepare Pt/Al <subscript>2</subscript> O <subscript>3</subscript> nanozymes. Through the Pt/Al <subscript>2</subscript> O <subscript>3</subscript> samples, we further proved that the distribution of the Pt clusters and the amount of the medium acid sites can significantly influence the peroxidase-like activity. Then the Pt/Al <subscript>2</subscript> O <subscript>3</subscript> sample was used for the detection of glucose. And as low as 0.96 μM glucose could be detected with a linear range from 5-60 μM via our method. This work showed the great potential applications of the easily prepared Pt/Al <subscript>2</subscript> O <subscript>3</subscript> samples in varieties of simple, robust, and easy-to-make analytical approaches in the future.<br /> (© 2023 Wiley-VCH GmbH.)

Subjects :: Peroxidase chemistry
Peroxidase metabolism
Oxidation-Reduction
Nanostructures chemistry
Platinum chemistry
Aluminum Oxide chemistry
Glucose analysis
Glucose chemistry
Biomimetic Materials chemistry

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