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Role of the Insulin-like Growth Factor (IGF) Axis in Diseases.

Authors :
Perks CM
Source :
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 30; Vol. 24 (23). Date of Electronic Publication: 2023 Nov 30.
Publication Year :
2023

Abstract

The insulin-like growth factor axis is a multifaceted, complex system that comprises two ligands, IGF-I and IGF-II, receptors (IGF-1R, IGF-IIR, insulin receptor isoforms IR-A and B, and hybrid receptors) six high affinity IGF-binding proteins (IGFBPs 1-6), and IGFBP proteases [...].

Subjects

Subjects :
Insulin-Like Growth Factor I metabolism
Insulin-Like Growth Factor Binding Proteins metabolism
Protein Binding
Insulin-Like Growth Factor Binding Protein 6 metabolism
Insulin-Like Growth Factor II genetics
Insulin-Like Growth Factor II metabolism

Details

Language :
English
ISSN :
1422-0067
Volume :
24
Issue :
23
Database :
MEDLINE
Journal :
International journal of molecular sciences
Publication Type :
Editorial & Opinion
Accession number :
38069291
Full Text :
https://doi.org/10.3390/ijms242316969
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