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[The nonadrenergic noncholinergic system in the regulation of bronchial tonus].
- Source :
-
Minerva medica [Minerva Med] 1986 Dec 22; Vol. 77 (49-50), pp. 2299-306. - Publication Year :
- 1986
-
Abstract
- Bronchial release appears to be regulated by the nonadrenergic noncholinergic system whose transmitter is very probably VIP. In vivo and in vitro studies were conducted to discover whether peptide modifies basic function and/or bronchial spasm provoked by histamine. The data collected show that VIP failed to cause bronchodilation but protects against histamine induced bronchoconstriction both in vivo and in vitro.
- Subjects :
- Adult
Asthma physiopathology
Bronchi drug effects
Bronchi innervation
Bronchial Spasm chemically induced
Histamine
Humans
In Vitro Techniques
Male
Middle Aged
Spirometry
Vasoactive Intestinal Peptide pharmacology
Vasoactive Intestinal Peptide physiology
Bronchi physiology
Muscle Tonus drug effects
Subjects
Details
- Language :
- Italian
- ISSN :
- 0026-4806
- Volume :
- 77
- Issue :
- 49-50
- Database :
- MEDLINE
- Journal :
- Minerva medica
- Publication Type :
- Academic Journal
- Accession number :
- 3808386