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Redox-Neutral Cyclization of 2-Isocyanobiaryls through Photoredox/PPh 3 Dual Catalysis.
- Source :
-
Organic letters [Org Lett] 2023 Dec 29; Vol. 25 (51), pp. 9186-9190. Date of Electronic Publication: 2023 Dec 15. - Publication Year :
- 2023
-
Abstract
- The photoredox/PPh <subscript>3</subscript> -mediated cyclization of 2-isocyanobiaryls has been developed. A substantial range of functional-group-rich phenanthridine derivatives were synthesized at room temperature in a highly selective and atom-economic manner. Mechanistic studies suggested that the cyclization process is probably mediated both by Ph <subscript>3</subscript> P radical cation with key 1,2-hydride transfer and hydrogen atom generated through O-H bond homolytic cleavage of Ph <subscript>3</subscript> P-OH radical intermediate.
Details
- Language :
- English
- ISSN :
- 1523-7052
- Volume :
- 25
- Issue :
- 51
- Database :
- MEDLINE
- Journal :
- Organic letters
- Publication Type :
- Academic Journal
- Accession number :
- 38100717
- Full Text :
- https://doi.org/10.1021/acs.orglett.3c03744