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Long-term outcomes of patients with oral cavity cancer receiving postoperative radiotherapy after salvage neck dissection for cervical lymph node recurrence.
- Source :
-
Head & neck [Head Neck] 2024 Mar; Vol. 46 (3), pp. 541-551. Date of Electronic Publication: 2023 Dec 18. - Publication Year :
- 2024
-
Abstract
- Backgrounds: We aimed to clarify the outcomes of postoperative radiotherapy (PORT) after salvage neck dissection for cervical lymph node (LN) recurrence in oral cavity cancer.<br />Methods: We retrospectively evaluated overall survival (OS), recurrence-free survival (RFS), recurrence patterns, and adverse events of 51 patients with high-risk features receiving PORT after salvage neck dissection between 2009 and 2019.<br />Results: After a median follow-up of 7.4 years from PORT initiation, the 7-year OS and RFS rates were 66.3% (95% CI: 54.0-81.3) and 54.6% (95% CI: 42.1-70.9), respectively. Age <70 years and isolated LN recurrence were significantly associated with longer OS and RFS. Among the 22 patients who experienced recurrence, 14 experienced recurrence within the radiation field. PORT-related grade 3 acute mucositis (35%) and late adverse events (osteoradionecrosis [4%] and laryngeal stenosis [2%]) were observed.<br />Conclusions: PORT after salvage neck dissection for cervical LN recurrence achieved good survival with acceptable toxicity.<br /> (© 2023 Wiley Periodicals LLC.)
- Subjects :
- Humans
Aged
Retrospective Studies
Lymph Nodes surgery
Lymph Nodes pathology
Neoplasm Recurrence, Local radiotherapy
Neoplasm Recurrence, Local surgery
Neoplasm Recurrence, Local pathology
Salvage Therapy
Lymph Node Excision
Neck Dissection
Mouth Neoplasms radiotherapy
Mouth Neoplasms surgery
Subjects
Details
- Language :
- English
- ISSN :
- 1097-0347
- Volume :
- 46
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Head & neck
- Publication Type :
- Academic Journal
- Accession number :
- 38108511
- Full Text :
- https://doi.org/10.1002/hed.27609