How to Surveil Perianal Paget's Disease: A Case Report.

Authors :: Al-Abid MA
Law C
Mor I
Source :: Cureus [Cureus] 2023 Dec 10; Vol. 15 (12), pp. e50282. Date of Electronic Publication: 2023 Dec 10 (Print Publication: 2023).
Publication Year :: 2023
Abstract: Perianal Paget's disease (PPD) is a rare manifestation of extramammary Paget's disease. It is characterized by the presence of malignant glandular epithelial cells within the squamous epithelium. There is a well-established but poorly understood association between PPD and underlying malignancy. Due to the rarity of the disease, there are no established guidelines for treatment or surveillance of PPD. We present the unusual case of a 73-year-old woman with primary PPD without an underlying malignant lesion. The rarity of the disease renders its management and surveillance an ongoing challenge. Our case of PPD without an underlying malignancy poses the question of the most appropriate surveillance for this rare disease.<br />Competing Interests: The authors have declared that no competing interests exist.<br /> (Copyright © 2023, Al-Abid et al.)