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The Role of the Gut Microbiota in Anorexia Nervosa in Children and Adults-Systematic Review.

Authors :
Anton-Păduraru DT
Trofin F
Nastase EV
Miftode RS
Miftode IL
Trandafirescu MF
Cojocaru E
Țarcă E
Mindru DE
Dorneanu OS
Source :
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 19; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 19.
Publication Year :
2023

Abstract

Among the factors incriminated in the appearance of eating disorders, intestinal microbiota has recently been implicated. Now there is evidence that the composition of gut microbiota is different in anorexia nervosa. We gathered many surveys on the changes in the profile of gut microbiota in patients with anorexia nervosa. This review comprehensively examines the contemporary experimental evidence concerning the bidirectional communication between gut microbiota and the brain. Drawing from recent breakthroughs in this area of research, we propose that the gut microbiota significantly contributes to the intricate interplay between the body and the brain, thereby contributing to overall healthy homeostasis while concurrently impacting disease risk, including anxiety and mood disorders. Particular attention is devoted to elucidating the structure and functional relevance of the gut microbiota in the context of Anorexia Nervosa.<br />Competing Interests: The authors declare no conflict of interest.

Details

Language :
English
ISSN :
1422-0067
Volume :
25
Issue :
1
Database :
MEDLINE
Journal :
International journal of molecular sciences
Publication Type :
Academic Journal
Accession number :
38203211
Full Text :
https://doi.org/10.3390/ijms25010041