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A Comparison of the Decline in Glomerular Filtration Rate between Elderly Patients with Diabetes and those without Diabetes in Southwest China.

Authors :
Yi QH
Wang HL
Hou Y
Xu L
Tian WL
Zhang YX
Xu YS
Shi JB
Source :
Endocrine, metabolic & immune disorders drug targets [Endocr Metab Immune Disord Drug Targets] 2024; Vol. 24 (12), pp. 1371-1376.
Publication Year :
2024

Abstract

Objective: To investigate the effect of high blood glucose on the decline in the estimated glomerular filtration rate (eGFR) in the elderly.<br />Methods: We compared the decline in eGFR of diabetic and non-diabetic groups in the noninterventional state and analyzed the effect of hyperglycemia on the decline in eGFR among the elderly in a retrospective analysis of 1,223 cases of elderly people aged 65 years or older with a 4-year follow-up period.<br />Results: The prevalence of diabetes in the elderly increased significantly from 12.67% in 2017 to 16.68% in 2021. The rate of decline in eGFR in patients with diabetes was higher than in the population without diabetes, at 9.29% and 5.32%, respectively (both p <0.05).<br />Conclusion: The results of this study revealed that the prevalence of diabetes in the elderly increased significantly, and there is a more rapid decrease in the eGFR levels in those with diabetes than those without diabetes.<br /> (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)

Details

Language :
English
ISSN :
2212-3873
Volume :
24
Issue :
12
Database :
MEDLINE
Journal :
Endocrine, metabolic & immune disorders drug targets
Publication Type :
Academic Journal
Accession number :
38243974
Full Text :
https://doi.org/10.2174/0118715303261963231228125548