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Manifestation of Pancytopenia Associated with COVID-19 as Paroxysmal Nocturnal Hemoglobinuria (PNH) and Aplastic Anemia (AA).

Authors :
Aguilar JJ
Dhillon V
Balasubramanian S
Source :
Hematology reports [Hematol Rep] 2024 Jan 17; Vol. 16 (1), pp. 42-49. Date of Electronic Publication: 2024 Jan 17.
Publication Year :
2024

Abstract

We report two cases of pancytopenia in patients after recovering from a mild COVID-19, now presenting as paroxysmal nocturnal hemoglobinuria (PNH) and aplastic anemia. These cases illustrate a common pathway whereby a viral trigger causes the clonal expansion of a hematological disorder. Although the association of both cases with COVID-19 is temporal and COVID-19 may be an incidental diagnosis, the growing evidence related to the hematological effects of SARS-CoV-2 infection highlights the need for further investigation into the hematological consequences of COVID-19, particularly in the post-pandemic era.

Details

Language :
English
ISSN :
2038-8322
Volume :
16
Issue :
1
Database :
MEDLINE
Journal :
Hematology reports
Publication Type :
Academic Journal
Accession number :
38247995
Full Text :
https://doi.org/10.3390/hematolrep16010005