Microlesion Effect Induced by Electrode Implantation in the Posteroventral Globus Pallidus Interna for Severe Dystonic Tics.

Authors :: Permana GI
Morishita T
Tanaka H
Iida H
Fujioka S
Abe H
Source :: Tremor and other hyperkinetic movements (New York, N.Y.) [Tremor Other Hyperkinet Mov (N Y)] 2024 Jan 18; Vol. 14, pp. 5. Date of Electronic Publication: 2024 Jan 18 (Print Publication: 2024).
Publication Year :: 2024
Abstract: Background: Tourette syndrome (TS) is a neurologic condition characterized by motor and phonic tics. Dystonic tics, including blepharospasm, are considered atypical or unusual in severe TS.<br />Case Report: We report a severe case of TS with facial dystonic tics resembling blepharospasm in which the microlesion effect and a sustained therapeutic effect was observed with bilateral globus pallidus interna (GPi) deep brain stimulation (DBS).<br />Discussion: Bilateral GPi DBS can be beneficial for blepharospasm-like tics and severe symptoms of TS. The improvements seen can be explained by the microlesion effect induced by DBS lead placement in the GPi.<br />Competing Interests: The authors have no competing interests to declare.<br /> (Copyright: © 2024 The Author(s).)

Subjects :: Humans
Globus Pallidus
Electrodes
Tics therapy
Blepharospasm therapy
Tourette Syndrome therapy

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