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Inflammation as a New Therapeutic Target among Older Patients with Ischemic Heart Disease.

Authors :
Maidana D
Arroyo-Álvarez A
Arenas-Loriente A
Barreres-Martín G
Muñoz-Alfonso C
Bompart Berroteran D
Esteve Claramunt F
Blanco Del Burgo R
Cepas-Guillén P
Garcia-Blas S
Bonanad C
Source :
Journal of clinical medicine [J Clin Med] 2024 Jan 09; Vol. 13 (2). Date of Electronic Publication: 2024 Jan 09.
Publication Year :
2024

Abstract

Cardiovascular (CV) diseases remain a global health challenge, with ischemic heart disease (IHD) being the primary cause of both morbidity and mortality. Despite optimal pharmacological therapy, older patients with IHD exhibit an increased susceptibility to recurrent ischemic events, significantly impacting their prognosis. Inflammation is intricately linked with the aging process and plays a pivotal role in the evolution of atherosclerosis. Emerging anti-inflammatory therapies have shown promise in reducing ischemic events among high-risk populations. This review aims to explore the potential of targeted anti-inflammatory interventions in improving clinical outcomes and the quality of life for older patients with IHD.

Details

Language :
English
ISSN :
2077-0383
Volume :
13
Issue :
2
Database :
MEDLINE
Journal :
Journal of clinical medicine
Publication Type :
Academic Journal
Accession number :
38256497
Full Text :
https://doi.org/10.3390/jcm13020363