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Preoperative carcinoembryonic antigen and prognosis in patients with colorectal cancer.
- Source :
-
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 1985; Vol. 39 (7), pp. 392-5. - Publication Year :
- 1985
-
Abstract
- The relationship between preoperative CEA, Dukes staging and disease recurrence, was analyzed in 92 patients with colon-rectal cancer, all who underwent curative surgery. Sixty-five of the 92 patients were followed for 36 months. A significant increase in disease recurrence risk is observable starting from a preoperative CEA value of greater than 7.5 ng/ml; corresponding values as such are verified by a significant fall in the actuarial survival curve in comparison to the progress of the curves of the other two groups with lower CEA values. A statistically significant correlation between preoperative CEA and staging was not observed, while both parameters result statistically very reliable (p less than 0.001) for prognosis; preoperative CEA values, less or greater than 7.5 ng/ml can help to stratify the Dukes tumours with respect to the probability of recurrence.
- Subjects :
- Adenocarcinoma immunology
Adenocarcinoma surgery
Aged
Colonic Neoplasms surgery
Female
Follow-Up Studies
Humans
Male
Middle Aged
Neoplasm Recurrence, Local epidemiology
Neoplasm Staging
Postoperative Complications
Prognosis
Rectal Neoplasms surgery
Risk
Carcinoembryonic Antigen analysis
Colonic Neoplasms immunology
Rectal Neoplasms immunology
Subjects
Details
- Language :
- English
- ISSN :
- 0753-3322
- Volume :
- 39
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
- Publication Type :
- Academic Journal
- Accession number :
- 3830268