Hypertrophic Cardiomyopathy: A Brief Overview.

Authors :: Braunwald E
Source :: The American journal of cardiology [Am J Cardiol] 2024 Feb 01; Vol. 212S, pp. S1-S3. Date of Electronic Publication: 2024 Jan 29.
Publication Year :: 2024
Abstract: Hypertrophic cardiomyopathy (HCM) is a complex, heterogeneous disorder that affects approximately 1 in every 500 persons worldwide and about 750,000 Americans. It is characterized by left ventricular hypertrophy that is usually asymmetric, with enlarged myocytes in disarray, unexplained by loading conditions. Obstruction to left ventricular outflow occurs in approximately 60% of patients. The natural history and cardiac morphology of HCM are quite heterogeneous. Although most patients with HCM are asymptomatic or mildly symptomatic, a minority are disabled by dyspnea, angina, or syncope, develop advanced heart failure, or die suddenly.<br />Competing Interests: Declaration of competing interest The author has no competing interests to declare.<br /> (Copyright © 2023 The Author(s). Published by Elsevier Inc. All rights reserved.)