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Evaluation after implementation of chemical bowel preparation for surgical site infections in elective colorectal cancer surgery and role of antimicrobial stewardship pharmacist: Retrospective cohort study.
- Source :
-
Journal of pharmaceutical health care and sciences [J Pharm Health Care Sci] 2024 Feb 19; Vol. 10 (1), pp. 11. Date of Electronic Publication: 2024 Feb 19. - Publication Year :
- 2024
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Abstract
- Background: We evaluated the predictive factors for surgical site infections (SSIs) in elective colorectal cancer surgery and the role of antimicrobial stewardship (AS) pharmacists in modifying the clinical pathway.<br />Main Body: Between February 2017 and January 2022, 414 elective colorectal cancer surgeries were performed. The results of multivariate analysis by SSI incidence were adjusted odds ratio (aOR): 0.45; 95% confidence interval (CI): 0.22-0.96 (P = 0.039) for sex (female), aOR: 0.27; 95% CI: 0.13-0.58 (P < 0.001) for laparoscopy, aOR: 0.42; 95% CI: 0.19-0.91 (P = 0.029) for chemical bowel preparation. The median (interquartile range) postoperative length of stay was 12 (10.0-18.5) vs. 10 (9.0-13.0) days before and after the clinical pathway was modified (P < 0.001).<br />Conclusion: The role of AS pharmacists was primarily to conduct a literature search to explore whether SSIs could be ameliorated by pharmacotherapy, coordinate the addition of chemical bowel preparation, and epidemiologically confirm their effectiveness.<br /> (© 2024. The Author(s).)
Details
- Language :
- English
- ISSN :
- 2055-0294
- Volume :
- 10
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Journal of pharmaceutical health care and sciences
- Publication Type :
- Academic Journal
- Accession number :
- 38374208
- Full Text :
- https://doi.org/10.1186/s40780-024-00333-1