A noncoding role of coding mRNA in monogenic olfactory receptor choice.

Authors :: Hao Y
Qian KY
Li Q
Source :: Trends in neurosciences [Trends Neurosci] 2024 Mar; Vol. 47 (3), pp. 167-169. Date of Electronic Publication: 2024 Feb 19.
Publication Year :: 2024
Abstract: In a recent study, Pourmorady and colleagues uncovered a noncoding role for olfactory receptor (OR)-coding mRNA in mediating nuclear architecture and singular OR choice. The OR mRNAs reinforce the prevailing enhancer hub and inhibit other competitors, facilitating transition from polygenic to singular OR expression.<br />Competing Interests: Declaration of interests The authors declare no competing interests.<br /> (Copyright © 2024 Elsevier Ltd. All rights reserved.)