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Diagnosis and management of smouldering myeloma: A British Society for Haematology Good Practice Paper.
- Source :
-
British journal of haematology [Br J Haematol] 2024 Apr; Vol. 204 (4), pp. 1193-1206. Date of Electronic Publication: 2024 Feb 23. - Publication Year :
- 2024
-
Abstract
- Multiple myeloma is a bone marrow-based plasma cell tumour that develops from asymptomatic pre-cursor conditions smouldering myeloma and monoclonal gammopathy of uncertain significance and all are characterised by the presence of a monoclonal protein in the blood. Diagnosis and distinction between these conditions is based on blood tests, the bone marrow biopsy and cross sectional imaging. There are various risk stratification models that group patients with smouldering myeloma into risk groups based on risk of progression to symptomatic disease. Management is mainly observational for patients with smouldering myeloma although clinical trials for high-risk disease may be available. Restaging is required if evidence for progression.<br /> (© 2024 British Society for Haematology and John Wiley & Sons Ltd.)
- Subjects :
- Humans
Plasma Cells pathology
Disease Progression
Multiple Myeloma diagnosis
Multiple Myeloma therapy
Multiple Myeloma pathology
Monoclonal Gammopathy of Undetermined Significance diagnosis
Monoclonal Gammopathy of Undetermined Significance therapy
Monoclonal Gammopathy of Undetermined Significance pathology
Smoldering Multiple Myeloma diagnosis
Smoldering Multiple Myeloma therapy
Smoldering Multiple Myeloma pathology
Hematology
Subjects
Details
- Language :
- English
- ISSN :
- 1365-2141
- Volume :
- 204
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- British journal of haematology
- Publication Type :
- Periodical
- Accession number :
- 38393718
- Full Text :
- https://doi.org/10.1111/bjh.19333