Patient-reported outcomes and apixaban therapy in older patients.

Competing Interests: Declaration of competing interest Giancarlo Agnelli, one of the Authors of the manuscript, is the Editor-in-Chief of the European Journal of Internal Medicine. Giuseppe Di Pasquale, Giancarlo Agnelli and Niccolò Marchionni received remuneration from Pfizer and Bristol Myers Squibb for their services as a member of the Steering Committee of the APULEIO Study. Among The APULEIO Study Investigators, Alessandro Bigagli is Disease Area Head of Bristol-Myers Squibb, Italy; Jessica Marcuccitti is Disease Area Specialist – Cardiovascular of Bristol-Myers Squibb, Italy; Barbara Capaccetti, is Country Medical Director of Pfizer, Italy; Giuseppe Vuolo is Medical Affairs Scientist Line Manager Cardiovascular & Global Brand of Pfizer, Italy; Roberta Sergi, MD is Medical Affairs Scientist Internal Medicine of Pfizer, Italy; Martina Di Santoro is Medical Affairs Scientist Cardiovascular of Pfizer, Italy. The other Authors have no conflict of interest to disclose.