PREVALENCE OF ATOPIC DISORDERS AMONG PEDIATRIC PATIENTS WITH PULMONARY AND DISSEMINATED COCCIDIOIDOMYCOSIS.

Authors :: Zhang S
LaBere B
Woodward JV
Ballan W
Perry KW
Sacco K
Source :: The Pediatric infectious disease journal [Pediatr Infect Dis J] 2024 Mar 22. Date of Electronic Publication: 2024 Mar 22.
Publication Year :: 2024
Publisher :: Ahead of Print
Abstract: Type 2 inflammatory responses are associated with worse prognosis in coccidioidomycosis. It is unclear whether patients with preexisting type 2 inflammation and atopic disorders are predisposed to disseminated coccidioidomycosis. A retrospective analysis of pediatric patients with disseminated coccidioidomycosis revealed no significant difference in the history of atopic disorders or eosinophilia as compared to those with isolated pulmonary disease. Tissue-specific type 2 responses may still play a role in coccidioidomycosis immune dysregulation, and further investigation is needed.<br />Competing Interests: The authors have no funding or conflicts of interest to disclose.<br /> (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)

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