Amniotic membrane transplantation as part of a multimodal management approach to Streptococcus pyogenes necrotizing keratoconjunctivitis.

Authors :: Ruland KL
Beneschott N
Creech CB
Umfress A
Source :: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus [J AAPOS] 2024 Jun; Vol. 28 (3), pp. 103900. Date of Electronic Publication: 2024 Mar 25.
Publication Year :: 2024
Abstract: Streptococcus pyogenes (group A beta-hemolytic Streptococcus, GABHS) causes a range of human infections, including necrotizing fasciitis and toxic shock syndrome, because it produces exotoxins that damage host cells, facilitate immune evasion, and serve as T cell superantigens. GABHS conjunctivitis is rare. We report a case of membranous conjunctivitis in a 3-year-old child who was treated with a combination of targeted bactericidal antimicrobials, toxin-synthesis inhibition, and amniotic membrane transplantation.<br /> (Copyright © 2024 American Association for Pediatric Ophthalmology and Strabismus. Published by Elsevier Inc. All rights reserved.)

Language :: English
ISSN :: 1528-3933
Volume :: 28
Issue :: 3
Database :: MEDLINE
Journal :: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus
Publication Type :: Academic Journal
Accession number :: 38537895
Full Text :: https://doi.org/10.1016/j.jaapos.2024.103900

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