Functional roles of circular RNAs in lung injury.

Authors :: Gao FF
Chen DQ
Jiang YT
Han CF
Lin BY
Yang Z
Quan JH
Xiong YH
Chen XT
Source :: Frontiers in pharmacology [Front Pharmacol] 2024 Mar 27; Vol. 15, pp. 1354806. Date of Electronic Publication: 2024 Mar 27 (Print Publication: 2024).
Publication Year :: 2024
Abstract: Lung injury leads to respiratory dysfunction, low quality of life, and even life-threatening conditions. Circular RNAs (circRNAs) are endogenous RNAs produced by selective RNA splicing. Studies have reported their involvement in the progression of lung injury. Understanding the roles of circRNAs in lung injury may aid in elucidating the underlying mechanisms and provide new therapeutic targets. Thus, in this review, we aimed to summarize and discuss the characteristics and biological functions of circRNAs, and their roles in lung injury from existing research, to provide a theoretical basis for the use of circRNAs as a diagnostic and therapeutic target for lung injury.<br />Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.<br /> (Copyright © 2024 Gao, Chen, Jiang, Han, Lin, Yang, Quan, Xiong and Chen.)