Evolution and Antigenic Differentiation of Avian Influenza A(H7N9) Virus, China.

Authors :: Liu Y
Chen Y
Yang Z
Lin Y
Fu S
Chen J
Xu L
Liu T
Niu B
Huang Q
Liu H
Zheng C
Liao M
Jia W
Source :: Emerging infectious diseases [Emerg Infect Dis] 2024 Jun; Vol. 30 (6), pp. 1218-1222. Date of Electronic Publication: 2024 Apr 19.
Publication Year :: 2024
Abstract: We characterized the evolution and molecular characteristics of avian influenza A(H7N9) viruses isolated in China during 2021-2023. We systematically analyzed the 10-year evolution of the hemagglutinin gene to determine the evolutionary branch. Our results showed recent antigenic drift, providing crucial clues for updating the H7N9 vaccine and disease prevention and control.

Subjects :: China epidemiology
Animals
Humans
Birds virology
Antigenic Variation
Influenza A Virus, H7N9 Subtype genetics
Influenza A Virus, H7N9 Subtype immunology
Evolution, Molecular
Influenza in Birds virology
Influenza in Birds epidemiology
Phylogeny
Hemagglutinin Glycoproteins, Influenza Virus genetics
Hemagglutinin Glycoproteins, Influenza Virus immunology
Influenza, Human epidemiology
Influenza, Human virology
Influenza, Human immunology
Antigens, Viral immunology
Antigens, Viral genetics

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