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Economic burden of pertussis in children: A single-center analysis in Hangzhou, China.
- Source :
-
Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2024 Dec 31; Vol. 20 (1), pp. 2343199. Date of Electronic Publication: 2024 Apr 22. - Publication Year :
- 2024
-
Abstract
- The "reemergence of pertussis" has elicited international concerns, occurring paradoxically amidst the expansion of immunization programs. This study was aimed to evaluate quantitatively the economic burden and identify the determinants that influence the cost associated with treating pertussis in Chinese children. We evaluated the economic burden by Chinese children diagnosed with pertussis at the Children's Hospital, Zhejiang University School of Medicine in 2022. Direct medical expenses and the utilization of medical resources attributed to pertussis were calculated. A generalized linear regression model was applied to analyze the determinants that were associated with the direct medical expenses among patients. Among the 1110 pertussis patients included in the study, 1060 were outpatients and 50 were inpatients. The average direct medical cost was ¥1878.70(i.e. $279.33). Living in urban areas (OR:1.27, p = .04), complications (OR:1.40, p < .001), hospitalization (OR:10.04, p < .001), and ≥ 3 medical visits (OR:3.71, p < .001) were associated with increased direct medical expenses. Having received four doses of the pertussis vaccine was associated with reduced direct medical expenses (OR:0.81, p = .04). This study underscores a substantial economic burden of pertussis in Hangzhou, with pronounced implications for patients residing in urban areas, experiencing complications, requiring hospitalization, having multiple medical consultations, or lacking comprehensive pertussis vaccination.
- Subjects :
- Humans
China epidemiology
Male
Female
Child, Preschool
Infant
Child
Adolescent
Vaccination economics
Whooping Cough economics
Whooping Cough epidemiology
Whooping Cough prevention & control
Cost of Illness
Pertussis Vaccine economics
Pertussis Vaccine administration & dosage
Health Care Costs statistics & numerical data
Hospitalization economics
Hospitalization statistics & numerical data
Subjects
Details
- Language :
- English
- ISSN :
- 2164-554X
- Volume :
- 20
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Human vaccines & immunotherapeutics
- Publication Type :
- Academic Journal
- Accession number :
- 38647026
- Full Text :
- https://doi.org/10.1080/21645515.2024.2343199