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The H3K4 demethylase JMJ1 is required for proper timing of flowering in Brachypodium distachyon.
- Source :
-
The Plant cell [Plant Cell] 2024 Jul 02; Vol. 36 (7), pp. 2729-2745. - Publication Year :
- 2024
-
Abstract
- Flowering is a key developmental transition in the plant life cycle. In temperate climates, flowering often occurs in response to the perception of seasonal cues such as changes in day-length and temperature. However, the mechanisms that have evolved to control the timing of flowering in temperate grasses are not fully understood. We identified a Brachypodium distachyon mutant whose flowering is delayed under inductive long-day conditions due to a mutation in the JMJ1 gene, which encodes a Jumonji domain-containing protein. JMJ1 is a histone demethylase that mainly demethylates H3K4me2 and H3K4me3 in vitro and in vivo. Analysis of the genome-wide distribution of H3K4me1, H3K4me2, and H3K4me3 in wild-type plants by chromatin immunoprecipitation and sequencing combined with RNA sequencing revealed that H3K4m1 and H3K4me3 are positively associated with gene transcript levels, whereas H3K4me2 is negatively correlated with transcript levels. Furthermore, JMJ1 directly binds to the chromatin of the flowering regulator genes VRN1 and ID1 and affects their transcription by modifying their H3K4me2 and H3K4me3 levels. Genetic analyses indicated that JMJ1 promotes flowering by activating VRN1 expression. Our study reveals a role for JMJ1-mediated chromatin modification in the proper timing of flowering in B. distachyon.<br />Competing Interests: Conflict of interest statement. The authors declare no competing interest.<br /> (© The Author(s) 2024. Published by Oxford University Press on behalf of American Society of Plant Biologists. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our siteāfor further information please contact journals.permissions@oup.com.)
- Subjects :
- Mutation genetics
Jumonji Domain-Containing Histone Demethylases genetics
Jumonji Domain-Containing Histone Demethylases metabolism
Chromatin metabolism
Chromatin genetics
Brachypodium genetics
Brachypodium physiology
Flowers genetics
Flowers physiology
Flowers growth & development
Gene Expression Regulation, Plant
Plant Proteins genetics
Plant Proteins metabolism
Histones metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 1532-298X
- Volume :
- 36
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- The Plant cell
- Publication Type :
- Academic Journal
- Accession number :
- 38652680
- Full Text :
- https://doi.org/10.1093/plcell/koae124