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Azidomethylation of Nucleobases and Related N -Heterocycles, Benzazoles, and Bis(arene)sulfonimides Using Azidomethyl Esters with Silyl Triflates.

Authors :
Sawahata R
Takagi Y
Kitamura Y
Source :
Organic letters [Org Lett] 2024 May 10; Vol. 26 (18), pp. 3806-3809. Date of Electronic Publication: 2024 Apr 25.
Publication Year :
2024

Abstract

An efficient method for the azidomethylation of amines using azidomethyl esters with silyl triflates is described. This protocol enables the azidomethylation of various amines that can be activated with silyl groups, including nucleobases.

Details

Language :
English
ISSN :
1523-7052
Volume :
26
Issue :
18
Database :
MEDLINE
Journal :
Organic letters
Publication Type :
Academic Journal
Accession number :
38662603
Full Text :
https://doi.org/10.1021/acs.orglett.4c00938