InsT-ALLing CD7 chimeric antigen receptors before transplantation.

Authors :: Delgado J
Source :: British journal of haematology [Br J Haematol] 2024 Jun; Vol. 204 (6), pp. 2155-2156. Date of Electronic Publication: 2024 Apr 26.
Publication Year :: 2024
Abstract: In their paper, the authors present their experience with the use of chimeric antigen receptor T cells targeting CD7 as a bridge to allogeneic haematopoietic cell transplantation in patients with relapsed/refractory T-cell acute lymphoblastic leukaemia/lymphoblastic lymphoma. Commentary on: Cao et al. A safety and efficacy study of allogeneic haematopoietic stem cell transplantation for refractory and relapsed T-cell acute lymphoblastic leukaemia/lymphoblastic lymphoma patients who achieved complete remission after autologous CD7 chimeric antigen receptor T-cell therapy. Br J Haematol 2024;204:2351-2364.<br /> (© 2024 British Society for Haematology and John Wiley & Sons Ltd.)