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Diagnosis of Central Precocious Puberty.
- Source :
-
Endocrinology and metabolism clinics of North America [Endocrinol Metab Clin North Am] 2024 Jun; Vol. 53 (2), pp. 217-227. Date of Electronic Publication: 2024 Mar 04. - Publication Year :
- 2024
-
Abstract
- A thorough history and physical examination including Tanner staging and growth assessments can guide differential diagnosis and aid in the evaluation of precocious puberty. Basal luteinizing hormone levels measured using a highly sensitive assay can be helpful in diagnosing central precocious puberty (CPP). Brain MRI is indicated with males diagnosed with CPP and females under the age of 6 with CPP. As more information becomes available regarding the genetic etiologies of CPP, genetic testing may preclude the need for imaging studies and other hormonal testing, especially in familial cases.<br />Competing Interests: Disclosure K. Bangalore Krishna has no relevant disclosures to this article. L.A. Silverman has been a consultant for Tolmar, a Data and Safety Monitoring Board member for Myovant, and with the Speaker’s Bureau for Abbvie.<br /> (Copyright © 2024 Elsevier Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1558-4410
- Volume :
- 53
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Endocrinology and metabolism clinics of North America
- Publication Type :
- Academic Journal
- Accession number :
- 38677865
- Full Text :
- https://doi.org/10.1016/j.ecl.2024.02.002