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HPLC-Based Automated Synthesis and Purification of Carbohydrates.
- Source :
-
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2024 Aug 01; Vol. 30 (43), pp. e202401214. Date of Electronic Publication: 2024 May 29. - Publication Year :
- 2024
-
Abstract
- Reported herein is a new HPLC-based automated synthesizer (HPLC-A) capable of a temperature-controlled synthesis and purification of carbohydrates. The developed platform allows to perform various protecting group manipulations as well as the synthesis of O- and N-glycosides. A fully automated synthesis and purification was showcased in application to different carbohydrate derivatives including glycosides, oligosaccharides, glycopeptides, glycolipids, and nucleosides.<br /> (© 2024 Wiley-VCH GmbH.)
- Subjects :
- Chromatography, High Pressure Liquid
Glycosides chemistry
Glycosides chemical synthesis
Glycolipids chemistry
Glycolipids chemical synthesis
Glycolipids isolation & purification
Glycopeptides chemistry
Glycopeptides chemical synthesis
Nucleosides chemistry
Nucleosides chemical synthesis
Automation
Temperature
Carbohydrates chemistry
Oligosaccharides chemical synthesis
Oligosaccharides chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1521-3765
- Volume :
- 30
- Issue :
- 43
- Database :
- MEDLINE
- Journal :
- Chemistry (Weinheim an der Bergstrasse, Germany)
- Publication Type :
- Academic Journal
- Accession number :
- 38684455
- Full Text :
- https://doi.org/10.1002/chem.202401214